TILIDIN GELBE LISTE FUNDAMENTALS EXPLAINED

Right after oral administration, tilidine is promptly absorbed. It can be issue to a pronounced initial-pass effect. The conversion of tilidine to the greater potent Lively metabolite nortilidine takes place While using the involvement of CYP3A4 and CYP2C19. Inhibition of such enzymes may possibly Hence change the efficacy and tolerability profile